แขนงวิชาภูมิคุ้มกันวิทยาคลินิก

ศาสตราจารย์ ดร.วัชระ  กสิณฤกษ์

แขนงวิชาภูมิคุ้มกันวิทยาคลินิก
  :  watchara.k@cmu.ac.th
  :  053-935080

ประวัติการศึกษา

- Ph.D. (Immunology) - วท.ม. (จุลชีววิทยา) - วท.บ. (เทคนิคการแพทย์)

  • 1. Jindaphun K, Takheaw N, Laopajon W, Pata S, Kasinrerk W. Toxicity effects of Cannabidiol (CBD) on immune cells. J Assoc Med Sci 2024;57(1):87-95.

  • 2. Chuensirikulchai K, Pata S, Laopajon W, Takheaw N, Kotemul K, Jindaphun K, Khummuang S, Kasinrerk W. Identification of different functions of CD8+ T cell subpopulations by a novel monoclonal antibody. Immunology 2024;2024(-):doi: 10.1111/imm.13826.

  • 3. Kotemul K, Kasinrerk W, Takheaw N. CD99 tumor associated antigen is a potential target for antibody therapy of T-cell acute lymphoblastic leukemia. Explor Target Antitumor Ther 2024;5(1):96-107. doi: 10.37349/etat.2024.00207.

  • 4. Jindaphun K, Takheaw N Chaochetdhapada P, Laopajon W, Kotemul K, Chaiwut R, Pata S, Kasinrerk W. Production of anti-human cannabinoid receptor 2 (CB2) monoclonal antibody using non-viral vector induced human CB2 expressing myeloma as an immunogen. Asian Pac J Allergy Immunol 2024;2024(-):doi: 10.12932/AP-020723-1646.

  • 5. Takheaw N, Kotemul K, Chaiwut R, Pata S, Laopajon W, Rangnoi K, Yamabhai M, Kasinrerk W. Transcriptome Analysis Reveals the Induction of Apoptosis-Related Genes by a Monoclonal Antibody against a New Epitope of CD99 on T-Acute Lymphoblastic Leukemia. Antibodies (Basel) 2024;13(2):42.

  • 6. Thongkum W, Klayprasert P, Semakul N, Jakmunee J, Kasinrerk W, Setshedi M, Sayed Y, Tayapiwatana C. Semi-quantification and potency verification of the HIV protease inhibitor based on the matrix-capsid protein immobilized nickel (II)/NTA-Tol/graphene oxide/SPCE electrochemical biosensor. ACS Omega 2023;8(20):17932-40.

  • 7. Takheaw N, Liwsrisakun C, Laopajon W, Pata S, Chiwong W, Inchai J, Duangjit P, Pothirat C, Bumroongkit C, Deesomchok A, Theerakittikul T, Limsukon A,Tajarernmuang P, Niyatiwatchanchai N, Trongtrakul K, Kasinrerk W. Levels and durability of neutralizing antibodies against SARS-CoV-2 Omicron and other variants after ChAdOx-1 or BNT162b2 booster in CoronaVac-primed elderly individuals. Heliyon 2023;9(4):e15653. doi 10.1016/j.heliyon.2023.e15653.

  • 8. Takheaw N, Jindaphun K, Pata S, Laopajon W, Kasinrerk W. Cannabinoid receptor 1 agonist ACEA and cannabinoid receptor 2 agonist GW833972A attenuates cell-mediated immunity by different biological mechanisms. Cells 2023;12(6):848. doi 10.3390/cells12060848.

  • 9. Tantakitti F, Pata S, Laopajon W, Kasinrerk W. Hidalgo-Bastida A. Production of high-value proteins under stringent cost constraints-The case of hollow fiber technology for cell culture. Processes 2023;11(3):889. doi 10.3390/pr11030889.

  • 10. Chaiwong W, Takheaw N, Pata S, Laopajon W, Duangjit P, Inchai J, Pothirat C, Bumroongkit C, Deesomchok A, Theerakittijul T, Limsukon A, Tajarernmuang P. Neutralizing antibody and T-cell responses against SARS-CoV-2 variants by heterologous CoronaVac/ChAdOx-1 vaccination in elderly subjects with chronic obstructive pulmonary disease. Vaccines 2023;41(40):5901–9.

  • 11. Laopajon W, Takheaw N, Kotemul K, Pata S, Hongeng S, Kasinrerk W. Chimeric single-chain variable fragment-human immunoglobulin G crystallizable fragment antibody against GD2 for neuroblastoma targeted immunotherapy. Explor Target Antitumor Ther 2023;4(6):1145-1156. doi: 10.37349/etat.2023.00188. Epub 202.

  • 12. Liwsrisakun C, Pata S, Laopajon W, Takheaw N, Chaiwong W, Duangjit P, Inchai J, Chuensirikulchai K, Cheyasawan P, Pothirat C, Bumroongkit C, Deesomchok A, Theerakittikul T, Limsukon A, Tajarernmuang P, Niyatiwatchanchai N, Trongtrakul K, Kasinrerk W. Humoral and cellular immune responses against SARS-CoV-2 variants of concern induced by heterologous CoronaVac/ChAdOx-1 versus homologous ChAdOx-1 vaccination in the elderly. Asian Pac J Allergy Immunol 2023;2023(-):doi 10.12932/AP-120822-1434.

  • 13. Kitro A, Sirikul W, Thongkum W, Soponpong S, Yasamut U, Kiratipaisarl W, Kosai A, Kasinrerk W, Tayapiwatana C, Srithanaviboonchai K. Dynamic of anti-spike receptor binding domain (RBD) levels and short-term adverse events following a heterologous booster dose of BNT162b2 after two doses of CoronaVac in Thai health care workers. Vaccines 2022;40(21):2915-24.

  • 14. Chaiwong W, Takheaw N, Laopajon W, Pata S, Duangjit P, Inchai J, Pothirat C, Bumroongkit C, Deesomchok A, Theerakittijul T, Limsukon A, Tajarernmuang P. Niyatiwatchanchai N, Trongtrakul K, Chuensirikulchai K, Cheyasawan P, Liwsrisakun C, Kasinrerk W. Neutralizing antibody and T-cell responses against SARS-CoV-2 wild-type and variants of concern in chronic obstructive pulmonary disease subjects after ChAdOx-1/ChAdOx-1 homologous vaccination: A preliminary study. Vaccines 2022;10(2):2176. doi 10.3390/vaccines10122176.

  • 15. Chaiwut R, Kasinrerk W. Very low concentration of lipopolysaccharide can induce the production of various cytokines and chemokines in human primary monocytes. BMC Res Notes 2022;15(1):42.

  • 16. Luangaram P, Tamdet C, Saengwong C, Prommool T, Kraivong R, Nilchan N, Punyadee N, Avirutnan P, Srisawat C, Malasit P, Kasinrerk W, Puttikhunt C. Differential critical residues on the overlapped region of the non-structural protein-1 recognized by flavivirus and dengue virus cross-reactive monoclonal antibodies. Sci Rep 2022;12(1):21548.

  • 17. Takheaw N, Liwsrisakun C, Chaiwong W, Laopajon W, Pata S, Inchai J, Duangjit P, Pothirat C, Bumroongkit C, Deesomchok A, Theerakittkul T, Limsukon A, Tajarernmuang P, Niyatiwatchanchai N, Trongtrakul K, Kasinrerk W. Correlation Analysis of Anti-SARS-CoV-2 RBD IgG and Neutralizing Antibody against SARS-CoV-2 Omicron Variants after Vaccination. Diagnostics (Basel) 2022;12(6):1315. doi 10.3390/diagnostics12061315.

  • 18. Yimcharoen M, Saikaew S, Wattananandkul U, Phunpae P, Intorasoot S, Kasinrerk W, Tayapiwatana C, Butr-Indr B. The regulation of ManLAM-related gene expression in Mycobacterium tuberculosis with different drug resistance profiles following isoniazid treatment. Infect Drug Resist 2022;5(15):399-412.

  • 19. Liwsrisakun C, Pata S, Laopajon W, Takheaw N, Chaiwong W, Inchai J, Pothirat C, Bumroongkit C, Deesomchok A, Theerakittikul T, Limsukon A, Tajarernmuang P, Niyatiwatchanchai N, Trongtrakul K, Chuensirikulchai K. Kasinrerk W. Neutralizing antibody and T cell responses against SARS-CoV-2 variants of concern following ChAdOx-1 or BNT162b2 boosting in the elderly previously immunized with CoronaVac vaccine. Immun Ageing 2022;19(1):24. doi 10.1186/s12979-022-00279-8.

  • 20. Pomlok K, Pata S, Kulaphisit M, Pangnuchar R, Wipasa J, Smith DR, Kasinrerk W, Lithanatudom P. An IgM monoclonal antibody against domain 1 of CD147 induces non-canonical RIPK-independent necroptosis in a cell type specific manner in hepatocellular carcinoma cells. Biochim Biophys Acta Mol Cell Res 2022;1869(9):119295. doi 10.1016/j.bbamcr.2022.119295..

  • 21. Pata S, Surinkaew S, Takheaw N, Laopajon W, Chuensirikulchai K, Kasinrerk W. Differential CD147 Functional epitopes on distinct leukocyte subsets. Front Immunol 2021;12(-):704309. doi 10.3389/fimmu.2021.704309.

  • 22. Leitner J, Mahasongkram K, Schatzlmaier P, Pfisterer K, Leksa V, Pata S, Kasinrerk W, Stockinger H, Steinberger P. Differentiation and activation of human CD4 T cells is associated with a gradual loss of myelin and lymphocyte protein. Eur J Immunol 2021;51(4):848-63.

  • 23. Takheaw N, Pata S, Laopajon W, Roytrakul S, Kasinrerk W. The presence of membrane bound CD99 ligands on leukocyte surface. BMC Res Notes 2020;13(1):496.


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