แขนงวิชาจุลทรรศนศาสตร์คลินิก

รองศาสตราจารย์ ดร.สาวิตรี  เจียมพานิชยกุล

แขนงวิชาจุลทรรศนศาสตร์คลินิก
  :  sawitree.chiampa@cmu.ac.th
  :  053-949237

ประวัติการศึกษา

  • วท.ด. (ชีวเคมี)
  • วท.ม. (ชีวเคมี)
  • วท.บ. (เทคนิคการแพทย์)

Research Expertise

  • Multidrug resistance in leukemia
  • Targeting leukemia stem cells
  • Natural products

  • 1. Khaodee W, Xiyuan G, Han MTT, Tayapiwatana C, Chiampanichayakul S, Anuchapreeda S, Cressey R. Transcriptomic analysis of glucosidase II beta subunit (GluIIß) knockout A549 cells reveals its roles in regulation of cell adhesion molecules (CAMs) and anti-tumor immunity. BMC Genomics 2024;25(1):82. doi: 10.1186/s12864-023-09888-z.
  • 2. Liu Y, Zhang L, Wang L, Tang X, Wan S, Huang Q, Ran M, Shen H, Yang Y, Chiampanichayakul S, Tima S, Anuchapreeda S, Wu J. Targeting CD38/ ADP-ribosyl cyclase as a novel therapeutic strategy for identification of three potent agonists for leukopenia treatment. Pharmacol Res 2024;200(-):107068. doi:10.1016/j.phrs.2024.107068.
  • 3. Sun X, He Z, Lu R, Liu Z, Chiampanichayakul S, Anuchapreeda S, Jiang J, Tima S, Zhong Z. Hyaluronic acid-modified liposome potentiated in-vivo anti-hepatocelluar carcinoma of icaritin. Front Pharmacol 2024;15(-):1437515. Doi:10.3389/fphar.2024.1437515.
  • 4. Wan S, Fan Q, Wu Y, Zhang J, Qiao G, Jiang N, Yang J, Liu Y, Li J, Chiampanichayakul S, Tima S, Tong F, Anuchapreeda S, Wu J. Curcumin-loaded platelet membrane bioinspired chitosan-modified liposome for effective cancer therapy. Pharmaceutics 2023;15(2):631. doi 10.3390/pharmaceutics15020631.
  • 5. Aung WL, Chaiyana C, Chiampanichayakul S, Anuchapreeda S, Tima S. Cordyceps militaris extracts inhibit FLT3 protein expression and induce cell cycle arrest in FLT3 overexpressing leukemic cell models. J Assoc Med Sci 2023;56(2):68-78.
  • 6. Anuchapreeda S, Shaengkhamnang B, Panyajai P, Chiampanichayakul S, Tima S, Klangsinsirikul P, Vongchan P, Tantiworawit A. Preservation of peripheral blood stem cells (CD34+/CD38-) for bone marrow transplantation in Thai lymphoma patients. Nat Life Sci Commun 2023;22(3):e2023044. doi 10.12982/NLSC.2023.044.
  • 7. Rueankham L, Panyajai P, Saiai A, Rungrojdakul M, Tima S, Chiampanichayakul S, Yeerong K, Somwongin S, Chaiyana W, Dejkriengkraikul P, Okonogi S, Katekunlaphan T, Anuchapreeda S. Biological activities of extracts and compounds from Thai Kae-Lae (Maclura cochinchinensis (Lour.) Corner). BMC Compl Med Therapies 2023;23(1):191. doi 10.1186/s12906-023-03979-w.
  • 8. Tima S, Tapingkae T, To-anun C, Noireung P, Intaparn P, Chaiyana W, Sirithunyalug J, Panyajai P, Viriyaadhammaa N, Nirachonkul W, Rueankham L, Aung WL, Chueahongthong F, Chiampanichayakul S, Anuchapreeda S. Antileukaemic cell proliferation and cytotoxic activity of edible golden Cordyceps (Cordyceps militaris) extracts. Evid-based Complement Altern Med 2022;2022(-):5347718.doi 10.1155/2022/5347718.
  • 9. Chueahongthong F, Tima S, Chiampanichayakul S, Dejkriengkraikul P, Okonogi S, Sasarom M, Rodwattanagul S, Berkland C, Anuchapreeda S. Doxorubicin-loaded polymeric micelles conjugated with CKR- and EVQ-FLT3 peptides for cytotoxicity in leukemic stem cells. Pharmaceutics 2022;14(10):2115. doi 10.3390/pharmaceutics14102115.
  • 10. Liu Y, Huang Y, Li J, Wan S, Jiang N, Yang J, Chiampanichayakul S, Tima S, Anuchapreeda S, Wu J. A comprehensive comparison of medication strategies for platinum-sensitive recurrent ovarian cancer: A Bayesian network meta-analysis. Front Pharmacol 2022;13(-):1010626. doi 10.3389/fphar.2022.1010626.
  • 11. Chueahongthong F, Tima S, Chiampanichayakul S, Berkland C, Anuchapreeda S. Co-treatments of edigle curcumin from turmeric rhizomes and chemotherapeutic drugs on cytotoxicity and FLT3 protein expression in leukemic stem cells. Molecules 2022;26(19):5785. doi 10.3390/molecules26195785.
  • 12. Wang F, Yang L, Xiao M, Zhang Z, Shen J, Anuchapreeda S, Tima S, Chiampanichayakul S, Xiao Z. PD-L1 regulates cell proliferation and apoptosis in acute myeloid leukemia by activativating PI3K-AKT signaling pathway. Sci Rep 2022;12(1):11444. doi 10.1038/s41598-022-15020-0.
  • 13. Panyajai P, Chueahongthong F, Viriyaadhammaa N, Nirachonkul W, Tima S, Chiampanichayakul S, Anuchapreeda S, Okonogi S. Anticancer activity of Zingiber ottensii essential oil and its nanoformulations. PLos One 2022;17(1):e0262335. doi 10.1371/journal.pone.0262335.
  • 14. Viriyaadhammaa N, Duangmano S, Saiai A, Tungjai M, Dejkriengkraikul P, Tima S, Chiampanichayakul S, Krise J, Anuchapreeda S. A novel drug modulator diarylheptanoid (trans-1,7-Diphenyl-5-hydroxy-1-heptene) from curcuma comosa rhizomes for P-glycoprotein function and apoptosis induction in K652/ADR leukemic cells. Intern J Mol Sci 2022;23(16):8898. doi 10.3390/ijms23168989.
  • 15. Wan S, Wu Y, Fan Q, Yang G, Hu H, Tima S, Chiampanichayakul S, Anuchapreeda S, Wu J. Bioinspired platelet-like nanovector for enhancing cancer therapy via P-selectin targeting. Pharmaceutics 2022;14(12):2614. doi 10.3390/pharmaceutics14122614.
  • 16. Sriyab S, Laosirisathian N, Punyoyai C, Anuchapreeda S, Tima S, Chiampanichayakul S, Chaiyana W. Nutricosmetic effects of Asparagus officinalis: a potent matrix metalloproteinase-1 inhibitor. Sci Rep 2021;11(1):8772. doi 10.1038/s41598-021-88340-2.
  • 17. Nirachonkul W, Ogonogi S, Thumvijit T, Chiampanichayakul S, Panyajai P, Anuchapreeda S, Tima S, Chiampanichayakul S. CD123-targeted nano-curcumin molecule enhances cytotoxic efficacy in leukemic stem cells. Nanomaterials 2021;11(11):2974. doi 10.3390/nano11112974.
  • 18. Saosathan S, Khounvong J, Rungrojsakul M, Katekunlaphan T, Tima S, Chiampanichyakul S, Berkland C, Anuchapreeda S. Costunolide and parthenolide from Champi Sirindhorn (Magnolia sirindhorniae) inhibit leukemic cell proliferation in K562 and Molt-4 cell lines. Nat Prod Res 2021;35(6):988-92.
  • 19. Chuathong W, Phomsakha Na Sakonnakhon W, Lilakhon A, Devahastin Na Ayudhaya N, Khaodee W, Tima S, Intasai N, Chaiwongsa R, Chiampanichayakul S, Punturee K, Cressey R. Beneficial effects of macaroni made with resistant starch type 4 from unripe banana and turmeric extract on blood clinical chemistry and gut microbiota of healthy rats. J Food Nutr Res 2021;9(7):329-41.
  • 20. Shaengkhamnang B, Panyajai P, Chiampanichayakul S, Tima S, Chaiwongsa R, Thumvijit T, Klangsinsirikul P, Tantiworawit A, Anuchapreeda S. Preservative methods for autologous peripheral blood stem cells collected from Thai patients with multiple myeloma. J Assoc Med Sci 2020;53(2):14-22.
  • 21. Viriyaadhammaa N, Sakai A, Neimkhum W, Nirachonkul W, Chiampanichayakul S, Tima S, Usuki T, Duangmano S, Anuchapreeda S. Cytotoxic and antiproliferative effects of diarylheptanoids isolated from Curcuma commas Rhizomes on leukemia cells. Molecules 2020;25(22):5476. doi 10.3390/MOLECULES25225476.
  • 22. Saosathan S, Khounvong J, Rungrojsakul M, Katekunlaphan T, Tima S, Chiampanichayakul S, Anuchapreeda S. Inhibitory effects of contunolide and parthenolide from Champi Sirindhorn (Magnolia siridhorniae) on FLT3 protein expression in EoL-1 leukemic cells. J Assoc Med Sci 2020;53(1):8-18.
  • 23. Anuchapreeda S, Rungrojsakul M, Tima S, Chiampanichayakul S, Krig SR. Co-activation of WT1 and AP-1 proteins on WT1 gene promoter to induce WT1 gene expression in K562 cells . Cell Signal 2019;53():339-47.
  • 24. Panyajai P, Tima S, Chiampanichayakul S, Anuchapreeda S. Dietary Turmeric Bisdemethoxycurcumin Suppresses Wilms' Tumor 1 and CD34 Protein Expressions in KG-1a Leukemic Stem Cells . Nutr Cancer 2019;71(7):1189-1200.
  • 25. Saosathan S, Khounvong J, Rungrojsakul M, Katekunlaphan T, Tima S, Chiampanichayakul S, Berkland C, Anuchapreeda S . Costunolide and parthenolide from Champi Sirindhorn (Magnolia sirindhorniae) inhibit leukemic cell proliferation in K562 and molt-4 cell lines . Nat Prod Res 2019;28():1-5.
  • 26. Somno A, Anuchapreeda S, Chruewkamlow N, Pata S, Kasinrerk W, Chiampanichayakul S . Involvement of CD147 on multidrug resistance through the regulation of P-glycoprotein expression in K562/ADR leukemic cell line. leuk Res Rep 2016;26(6):33-8.
  • 27. Pakdeepak K, Pata S, Chiampanichayakul S, Kasinrerk W, Tatu T. Production and characterization of monoclonal antibodies against α-globin chain-containing human hemoglobins for detecting α-thalassemia disease . J Immunoassay Immunochem 2016;37(6):564-71.
  • 28. Chruewkamlow N, Pata S, Mahasongkram K, Laopajon W, Kasinrerk W, Chiampanichayakul S . β3 subunit of Na,K ATPase regulates T cell activation with no involvement of Na,K ATPase activity. Immunobiology 2015;220(5):634-40.
  • 29. Apiratmateekul N, Pata S, Chiampanichayakul S, Kasinrerk W. Non-mitogen containing conditioned medium for hybridoma production and single cell cloning . Asian Pac J Allergy Immunol 2012;30(2):114-22.
  • 30. Chiampanichayakul S, Anuchapreeda S, Chruewkamlow N, Mahasongkram K, Thanaratanakorn P, Kasinrerk W . Production of monoclonal antibodies to P-glycoprotein: its application in detection of soluble and surface P-glycoprotein of leukemia patients . Int J Hematol 2010;92(2):326-33.
  • 31. Tayapiwatana C, Kuntaruk S, Tatu T, Chiampanichayakul S, Munkongdee T, Winichagoon P, Fuchareon S, Kasinrerk W . Simple method for screening of alpha-thalassaemia 1 carriers . Int J Hematol 2009;85(5):559-67.
  • 32. Khunkaewla P, Chiampanichayakul S, Yasamut U, Pata S, Kasinrerk W. Production, characterization, and functional analysis of newly established CD99 monoclonal antibodies MT99/1 and MT99/2 . Hybridoma (Larchmt) 2007;26(4):241-50.
  • 33. Chiampanichayakul S, Peng-in P, Khunkaewla P, Stockinger H, Kasinrerk W. CD147 contains different bioactive epitopes involving the regulation of cell adhesion and lymphocyte activation . Immunobiology 2006;211(3):167-78.
  • 34. Chiampanichayakul S, Khunkaewla P, Pata S, Kasinrerk W. Na, K ATPase beta3 subunit (CD298): association with alpha subunit and expression on peripheral blood cells . Tissue Antigens 2006;68(6):509-17.
  • 35. Kritratanasak S, Chiampanichayakul S, Kasinrerk W. Production of IgY anti-mouse IgG antibodies from chicken eggs . Asian Pac J Allergy Immunol 2004;22(1-2):61-8.
  • 36. Chiampanichayakul S, Szekeres A, Khunkaewla P, Moonsom S, Leksa V, Drbal K, Zlabinger GJ, Hofer-Warbinek R, Stockinger H, Kasinrerk W . Engagement of Na,K-ATPase beta3 subunit by a specific mAb suppresses T and B lymphocyte activation . Int Immunol 2002;14(12):1407-14.
  • 37. Chiampanichayakul S, Kataoka K, Arimochi H, Thumvijit S, Kuwahara T, Nakayama H, Vinitketkumnuen U, Ohnishi Y. Inhibitory effects of bitter melon (Momordica charantia Linn.) on bacterial mutagenesis and aberrant crypt focus formation in the rat colon . J Med Invest 2001;48(1-2):88-96.

  • - ยังไม่มีข้อมูล -

  • - ยังไม่มีข้อมูล -